Antimicrobial effect of chitosan nanoparticles on streptococcus mutans biofilms.

نویسندگان

  • Luis E Chávez de Paz
  • Anton Resin
  • Kenneth A Howard
  • Duncan S Sutherland
  • Peter L Wejse
چکیده

Nanoparticle complexes were prepared from chitosans of various molecular weights (MW) and degrees of deacetylation (DD). The antimicrobial effect was assessed by the Live/Dead BacLight technique in conjunction with confocal scanning laser microscopy (CSLM) and image analysis. Nanocomplexes prepared from chitosans with high MW showed a low antimicrobial effect (20 to 25% of cells damaged), whereas those prepared from low-MW chitosans showed high antimicrobial effect (>95% of cells damaged).

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عنوان ژورنال:
  • Applied and environmental microbiology

دوره 77 11  شماره 

صفحات  -

تاریخ انتشار 2011